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Volume CXXXIII, Number 8
November 2, 2001
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Anthrax and you: in Maine
JEFF BENSON, M.D.
STAFF WRITER

Dear Dr. Jeff: "Like all of us, we're very worried about the threat of anthrax. What is the situation up here Maine? How is the Health Center handling this bioterrorist threat?" -A Concerned Parent

Dear Concerned Parent: The threat of anthrax is of course frightening to us all. There are so many unknowns, so many imponderables, and the situation seems to change hourly.

There are also many things we do know and many reasons to feel reassured and protected, particularly here in Maine.

The numbers involved so far are very small. Nationally, there have been about 35 exposures, which have resulted in 16 infections. Ten people have developed inhalation anthrax, and four of those ten have died. Six people have developed the far less dangerous cutaneous disease, and four others are thought to have unconfirmed cutaneous infections.

In Maine, there have been no known exposures to anthrax and no known cases of anthrax infection. To date, about 105 packages have been tested for anthrax by the State lab, and all 105 were negative.

Without meaning to seem insensitive to the plight of any of the unfortunate victims of anthrax poisoning, allow me to point out that we can expect a full 20,000 people to die of the flu this winter. This is expected the timing and nature of the annual flu epidemic fully characterized, risk factors for developing complications of the illness well described, the clinical course of the disease well known, an effective preventive vaccine, diagnostic tests for influenza readily available, and antiviral medication readily available. At issue here is much more our health care and public health systems than extremely limited and unlikely exposures to aerosolized spores.

The microbiology of anthrax was described in depth by Dr. McBride last week in The Orient.

The Maine Bureau of Health would like us all to understand four key clinical facts about anthrax. First, anthrax is not contagious. It cannot be spread through personal contact. Second, anthrax infection is treatable, especially if the infection is caught early, or is cutaneous. Third, anthrax spores are very difficult to aerosolize effectively via an envelope or package. And finally, cutaneous anthrax is very difficult to contract through intact skin, especially after hand-washing.

Maine has a coordinated system of health, emergency management, and law enforcement agencies, which are monitoring and ready to address any potential threat from biological, chemical or nuclear terrorism. It is important to note that much of this system existed prior to September 11. Antibiotic and vaccine stockpiles, for instance, were created over two years ago as a component of emergency response plans that were elaborated more than three years ago.

We have all heard a lot about what to do and what not to do with suspicious mail and unknown powders. We may also need to understand a little more about nasal swab testing for anthrax. These are not clinical tests that detect incubating anthrax infections. These tests only measure possible exposure, within the previous 24 hours, to anthrax spores. They are epidemiologic tools, often criminal investigative tools, and not diagnostic tools. Federal and State health officials recommend nasal swab testing only for those who may have been exposed to a substance that has been proven to contain anthrax spores.

So far, thank goodness, no one in Maine has met the criterion for testing.
A positive nasal swab test would mean a full 60 day course of antibiotics. Fortunately, we now know that exposure to any of the currently isolated anthrax strains can be effectively treated with Doxycycline.

What else can we do, should we do? We should all get flu shots. As our Surgeon General has pointed out, most of us can avoid flu-like symptoms, the kind which might make us worry about early, prodromal anthrax, by simply getting a flu shot and preventing influenza infection. Production of flu vaccine may have gotten off to a late start this year, but there will be more vaccine available by late December than ever before. At the Health Center, we hope to start our flu vaccine clinics towards the end of this month. Flu shots will be available free of charge to students and for $5.00 to faculty, staff and community members.

We should also do our best to stay well informed. There are many web-based sources for up-to-date information about anthrax and bioterrorism. Many of the most helpful Centers for Disease Control and World Health Organization websites can be accessed via the Bureau of Health (www.state.me.us/dhs and click on "bioterrorism") or the University of Albany (www.albany.edu/sph/bt/index.html).

To all of our healths!

Jeff Benson, M.D.
Dudley Coe Health Center